Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

• Päätekijät: Kristoffer K. Hendel (Tekijä), Charlotte Bagger (Tekijä), Uffe H. Olesen (Tekijä), Christian Janfelt (Tekijä), Steen H. Hansen (Tekijä), Merete Haedersdal (Tekijä), Catharina M. Lerche (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...