Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

• मुख्य लेखकों: Kristoffer K. Hendel (लेखक), Charlotte Bagger (लेखक), Uffe H. Olesen (लेखक), Christian Janfelt (लेखक), Steen H. Hansen (लेखक), Merete Haedersdal (लेखक), Catharina M. Lerche (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...