Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

• 主要な著者: Kristoffer K. Hendel (著者), Charlotte Bagger (著者), Uffe H. Olesen (著者), Christian Janfelt (著者), Steen H. Hansen (著者), Merete Haedersdal (著者), Catharina M. Lerche (著者)
• フォーマット: 図書
• 出版事項: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...