Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

• Үндсэн зохиолчид: Kristoffer K. Hendel (Зохиогч), Charlotte Bagger (Зохиогч), Uffe H. Olesen (Зохиогч), Christian Janfelt (Зохиогч), Steen H. Hansen (Зохиогч), Merete Haedersdal (Зохиогч), Catharina M. Lerche (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...