Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

• Asıl Yazarlar: Kristoffer K. Hendel (Yazar), Charlotte Bagger (Yazar), Uffe H. Olesen (Yazar), Christian Janfelt (Yazar), Steen H. Hansen (Yazar), Merete Haedersdal (Yazar), Catharina M. Lerche (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...