Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• Prif Awduron: Ki-Sun Park (Awdur), Hyungjun Kim (Awdur), Hye Jin Kim (Awdur), Kang-In Lee (Awdur), Seo-Young Lee (Awdur), Jieun Kim (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2022-03-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...