Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• Main Authors: Ki-Sun Park (Author), Hyungjun Kim (Author), Hye Jin Kim (Author), Kang-In Lee (Author), Seo-Young Lee (Author), Jieun Kim (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-03-01T00:00:00Z.
• Fag: article
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Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...