Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• Autori principali: Ki-Sun Park (Autore), Hyungjun Kim (Autore), Hye Jin Kim (Autore), Kang-In Lee (Autore), Seo-Young Lee (Autore), Jieun Kim (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-03-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...