Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• Үндсэн зохиолчид: Ki-Sun Park (Зохиогч), Hyungjun Kim (Зохиогч), Hye Jin Kim (Зохиогч), Kang-In Lee (Зохиогч), Seo-Young Lee (Зохиогч), Jieun Kim (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2022-03-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...