Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• Główni autorzy: Ki-Sun Park (Autor), Hyungjun Kim (Autor), Hye Jin Kim (Autor), Kang-In Lee (Autor), Seo-Young Lee (Autor), Jieun Kim (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...