Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• Автори: Ki-Sun Park (Автор), Hyungjun Kim (Автор), Hye Jin Kim (Автор), Kang-In Lee (Автор), Seo-Young Lee (Автор), Jieun Kim (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2022-03-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...