Diagnostic strategy of metagenomic next-generation sequencing for gram negative bacteria in respiratory infections

• Main Authors: Wenyan Liang (Author), Qun Zhang (Author), Qian Qian (Author), Mingyue Wang (Author), Yuchen Ding (Author), Ji Zhou (Author), Yi Zhu (Author), Yu Jin (Author), Xuesong Chen (Author), Hui Kong (Author), Wei Song (Author), Xin Lu (Author), Xiaodong Wu (Author), Xiaoyong Xu (Author), Shanling Dai (Author), Wenkui Sun (Author)
• Format: Book
• Published: BMC, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Objective This study aims to identify the most effective diagnostic method for distinguishing pathogenic and non-pathogenic Gram-negative bacteria (GNB) in suspected pneumonia cases using metagenomic next-generation sequencing (mNGS) on bronchoalveolar lavage fluid (BALF) samples. Methods T...