DIAGNOSTIC VALUE OF STUDYING THE LEVELS OF PRO- AND ANTI-INFLAMMATORY CYTOKINES OF THE IMMUNE SYSTEM IN PATIENTS WITH BREAST CANCER

The diagnostic value of the serum levels of proinflammatory (TNF-α, IL-1β, IL-6, and IFN-γ) and anti-inflammatory (IL-4 and IL-10) cytokines of the immune system was studied in 54 patients with breast cancer (BC). Analysis identified the increased concen- trations of proinflammatory cytokines, such...

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Main Author: L. T. Alimkhodjaeva (Author)
Format: Book
Published: ABV-press, 2014-09-01T00:00:00Z.
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100 1 0 |a L. T. Alimkhodjaeva  |e author 
245 0 0 |a DIAGNOSTIC VALUE OF STUDYING THE LEVELS OF PRO- AND ANTI-INFLAMMATORY CYTOKINES OF THE IMMUNE SYSTEM IN PATIENTS WITH BREAST CANCER 
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500 |a 1994-4098 
500 |a 1999-8627 
500 |a 10.17650/1994-4098-2009-0-3-4-49-52 
520 |a The diagnostic value of the serum levels of proinflammatory (TNF-α, IL-1β, IL-6, and IFN-γ) and anti-inflammatory (IL-4 and IL-10) cytokines of the immune system was studied in 54 patients with breast cancer (BC). Analysis identified the increased concen- trations of proinflammatory cytokines, such as IL-1β, TNF-α, and IL-6, in the peripheral sera of BC patients.Analysis of anti-inflammatory cytokines in the peripheral sera of patients with BC also revealed a significant increase in the values of IL-4 and IL-10. The findings suggest that there is imbalance between cellular and humoral immunity factors, the study of which will be an important diagnostic criterion for BC. 
546 |a RU 
690 |a proinflammatory and anti-inflammatory cytokines 
690 |a immunity 
690 |a immunopathogenesis 
690 |a breast cancer 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Опухоли женской репродуктивной системы, Vol 0, Iss 3-4, Pp 49-52 (2014) 
787 0 |n https://ojrs.abvpress.ru/ojrs/article/view/314 
787 0 |n https://doaj.org/toc/1994-4098 
787 0 |n https://doaj.org/toc/1999-8627 
856 4 1 |u https://doaj.org/article/083bc4a0ba8a4e7b9981f1e40d121299  |z Connect to this object online.