Anti-atherosclerosis mechanisms associated with regulation of non-coding RNAs by active monomers of traditional Chinese medicine
Atherosclerosis is the leading cause of numerous cardiovascular diseases with a high mortality rate. Non-coding RNAs (ncRNAs), RNA molecules that do not encode proteins in human genome transcripts, are known to play crucial roles in various physiological and pathological processes. Recently, researc...
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Frontiers Media S.A.,
2023-11-01T00:00:00Z.
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|---|---|---|---|
| 001 | doaj_083ebb4b13aa4531aecd61d263bcdb6f | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Guoqing Liu |e author |
| 700 | 1 | 0 | |a Guoqing Liu |e author |
| 700 | 1 | 0 | |a Liqiang Tan |e author |
| 700 | 1 | 0 | |a Xiaona Zhao |e author |
| 700 | 1 | 0 | |a Xiaona Zhao |e author |
| 700 | 1 | 0 | |a Minghui Wang |e author |
| 700 | 1 | 0 | |a Minghui Wang |e author |
| 700 | 1 | 0 | |a Zejin Zhang |e author |
| 700 | 1 | 0 | |a Zejin Zhang |e author |
| 700 | 1 | 0 | |a Jing Zhang |e author |
| 700 | 1 | 0 | |a Honggang Gao |e author |
| 700 | 1 | 0 | |a Meifang Liu |e author |
| 700 | 1 | 0 | |a Wei Qin |e author |
| 245 | 0 | 0 | |a Anti-atherosclerosis mechanisms associated with regulation of non-coding RNAs by active monomers of traditional Chinese medicine |
| 260 | |b Frontiers Media S.A., |c 2023-11-01T00:00:00Z. | ||
| 500 | |a 1663-9812 | ||
| 500 | |a 10.3389/fphar.2023.1283494 | ||
| 520 | |a Atherosclerosis is the leading cause of numerous cardiovascular diseases with a high mortality rate. Non-coding RNAs (ncRNAs), RNA molecules that do not encode proteins in human genome transcripts, are known to play crucial roles in various physiological and pathological processes. Recently, researches on the regulation of atherosclerosis by ncRNAs, mainly including microRNAs, long non-coding RNAs, and circular RNAs, have gradually become a hot topic. Traditional Chinese medicine has been proved to be effective in treating cardiovascular diseases in China for a long time, and its active monomers have been found to target a variety of atherosclerosis-related ncRNAs. These active monomers of traditional Chinese medicine hold great potential as drugs for the treatment of atherosclerosis. Here, we summarized current advancement of the molecular pathways by which ncRNAs regulate atherosclerosis and mainly highlighted the mechanisms of traditional Chinese medicine monomers in regulating atherosclerosis through targeting ncRNAs. | ||
| 546 | |a EN | ||
| 690 | |a non-coding RNAs | ||
| 690 | |a traditional Chinese medicine | ||
| 690 | |a atherosclerosis | ||
| 690 | |a cardiovascular diseases | ||
| 690 | |a active monomer | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Frontiers in Pharmacology, Vol 14 (2023) | |
| 787 | 0 | |n https://www.frontiersin.org/articles/10.3389/fphar.2023.1283494/full | |
| 787 | 0 | |n https://doaj.org/toc/1663-9812 | |
| 856 | 4 | 1 | |u https://doaj.org/article/083ebb4b13aa4531aecd61d263bcdb6f |z Connect to this object online. |