Development of Inhalable ATRA-Loaded PLGA Nanoparticles as Host-Directed Immunotherapy against Tuberculosis

• Main Authors: Ahmad Z. Bahlool (Author), Sarinj Fattah (Author), Andrew O'Sullivan (Author), Brenton Cavanagh (Author), Ronan MacLoughlin (Author), Joseph Keane (Author), Mary P. O'Sullivan (Author), Sally-Ann Cryan (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Developing new effective treatment strategies to overcome the rise in multi-drug resistant tuberculosis cases (MDR-TB) represents a global challenge. A host-directed therapy (HDT), acting on the host immune response rather than <i>Mtb</i> directly, could address these resistance issues....