Novel insights into histone lysine methyltransferases in cancer therapy: From epigenetic regulation to selective drugs
The reversible and precise temporal and spatial regulation of histone lysine methyltransferases (KMTs) is essential for epigenome homeostasis. The dysregulation of KMTs is associated with tumor initiation, metastasis, chemoresistance, invasiveness, and the immune microenvironment. Therapeutically, t...
Saved in:
Main Authors: | Qili Liao (Author), Jie Yang (Author), Shengfang Ge (Author), Peiwei Chai (Author), Jiayan Fan (Author), Renbing Jia (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2023-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Histone lysine methyltransferases selectively restrict HIV in central memory T cells
by: C. Dobrowolski, et al.
Published: (2017) -
The epigenetic modifier lysine methyltransferase 2C is frequently mutated in gastric remnant carcinoma
by: Bo Sun, et al.
Published: (2023) -
Epigenetic drug library screening reveals targeting DOT1L abrogates NAD+ synthesis by reprogramming H3K79 methylation in uveal melanoma
by: Xiang Gu, et al.
Published: (2023) -
The Role and Mechanism of Lysine Methyltransferase and Arginine Methyltransferase in Kidney Diseases
by: Xun Zhou, et al.
Published: (2022) -
Role of histone methyltransferase SETDB1 in regulation of tumourigenesis and immune response
by: Zhipeng Zhao, et al.
Published: (2022)