Cholecystectomy is associated with a higher risk of irritable bowel syndrome in the UK Biobank: a prospective cohort study

• Main Authors: Jinyu Zhao (Author), Liang Tian (Author), Bin Xia (Author), Ningning Mi (Author), Qiangsheng He (Author), Man Yang (Author), Danni Wang (Author), Siqing Wu (Author), Zijun Li (Author), Shiyong Zhang (Author), Xianzhuo Zhang (Author), Ping Yue (Author), Yanyan Lin (Author), Haitong Zhao (Author), Baoping Zhang (Author), Zelong Ma (Author), Ningzu Jiang (Author), Matu Li (Author), Jinqiu Yuan (Author), Peng Nie (Author), Linzhi Lu (Author), Wenbo Meng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Recent studies have shown that bile acids are essential in irritable bowel syndrome (IBS) pathology, and cholecystectomy has direct effects on bile acid metabolism. However, whether cholecystectomy increases the risk of IBS remains unclear. We aimed to investigate the association between...