Loss of full-length pumilio 1 abrogates miRNA-221-induced gene p27 silencing-mediated cell proliferation in the heart
Upregulated expression of microRNA (miR)-221 is associated with downregulation of p27 and subsequent increased cell proliferation in a variety of human cancers. It is unknown whether miR-221 mimics could trigger neoplastic cellular proliferation. In vitro, we demonstrated miR-221 significantly downr...
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Main Authors: | Yue Zhou (Author), Denise YuEn Ng (Author), Arthur Mark Richards (Author), Peipei Wang (Author) |
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Format: | Book |
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Elsevier,
2022-03-01T00:00:00Z.
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