GYF-21, an Epoxide 2-(2-Phenethyl)-Chromone Derivative, Suppresses Innate and Adaptive Immunity via Inhibiting STAT1/3 and NF-κB Signaling Pathways

• Main Authors: Ran Guo (Author), Yun-Fang Zhao (Author), Jun Li (Author), Yu-Fan Gu (Author), Hui-Xia Huo (Author), Shan-Shan Li (Author), Yue-Lin Song (Author), Zhi-Xiang Zhu (Author), Peng-Fei Tu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multiple sclerosis is a chronic inflammatory autoimmune disease of the central nervous system characterized by demyelinating plaques and axonal loss. Inhibition on over activation of innate and adaptive immunity provides a rationale strategy for treatment of multiple sclerosis. In the present study,...