A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments

Nerium oleander is a popular ornamental plant grown in many tropical and subtropical countries and in the Mediterranean region. It is dangerous because it has been shown to contain several types of cardiac glycosides, and hence can cause cardiac arrhythmias resembling digoxin in their toxicologic ma...

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Main Authors: Mustafa Adem Tatlısu (Author), Elif İjlal Çekirdekçi (Author), Şükrü Akyüz (Author), Zekeriya Nurkalem (Author)
Format: Book
Published: KARE Publishing, 2015-11-01T00:00:00Z.
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LEADER 00000 am a22000003u 4500
001 doaj_0a6a60e291344ca0a2d8d8182d18254c
042 |a dc 
100 1 0 |a Mustafa Adem Tatlısu  |e author 
700 1 0 |a Elif İjlal Çekirdekçi  |e author 
700 1 0 |a Şükrü Akyüz  |e author 
700 1 0 |a Zekeriya Nurkalem  |e author 
245 0 0 |a A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments 
260 |b KARE Publishing,   |c 2015-11-01T00:00:00Z. 
500 |a 1016-5169 
500 |a 10.5543/tkda.2015.65848 
520 |a Nerium oleander is a popular ornamental plant grown in many tropical and subtropical countries and in the Mediterranean region. It is dangerous because it has been shown to contain several types of cardiac glycosides, and hence can cause cardiac arrhythmias resembling digoxin in their toxicologic manifestations. We report a patient presenting to our hospital with Mobitz type II atrioventricular block after drinking herbal tea prepared from oleander leaves. Three hours after admission, a 200-mg empiric dose of digoxin-specific Fab antibody fragments was administered intravenously over 30 minutes. A 12-lead electrocardiogram (ECG) revealed sinus rhythm at the end of infusion. After 72 hours, the patient was discharged without any symptoms. 
546 |a EN 
546 |a TR 
690 |a atrioventricular block 
690 |a nerium oleander 
690 |a digoxin/adverse effects 
690 |a Medicine 
690 |a R 
690 |a Internal medicine 
690 |a RC31-1245 
690 |a Diseases of the circulatory (Cardiovascular) system 
690 |a RC666-701 
655 7 |a article  |2 local 
786 0 |n Türk Kardiyoloji Derneği Arşivi, Vol 43, Iss 7, Pp 648-650 (2015) 
787 0 |n https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-65848 
787 0 |n https://doaj.org/toc/1016-5169 
856 4 1 |u https://doaj.org/article/0a6a60e291344ca0a2d8d8182d18254c  |z Connect to this object online.