Intraventricular ciprofloxacin usage in treatment of multidrug-resistant central nervous system infections: report of four cases

In recent years, multidrug-resistant microorganisms appear as important nosocomial pathogens which treatment is quite difficult. As sufficient drug levels could not be achieved in cerebrospinal fluid during intravenous antibiotic therapy for central nervous system infections and due to multidrug-res...

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Main Authors: Ayse Karaaslan (Author), Eda Kepenekli Kadayifçi (Author), Ozden Turel (Author), Demet Gedikbaşi Toprak (Author), Ahmet Soysal (Author), Mustafa Bakir (Author)
Format: Book
Published: MDPI AG, 2014-12-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Ayse Karaaslan  |e author 
700 1 0 |a Eda Kepenekli Kadayifçi  |e author 
700 1 0 |a Ozden Turel  |e author 
700 1 0 |a Demet Gedikbaşi Toprak  |e author 
700 1 0 |a Ahmet Soysal  |e author 
700 1 0 |a Mustafa Bakir  |e author 
245 0 0 |a Intraventricular ciprofloxacin usage in treatment of multidrug-resistant central nervous system infections: report of four cases 
260 |b MDPI AG,   |c 2014-12-01T00:00:00Z. 
500 |a 2036-749X 
500 |a 2036-7503 
500 |a 10.4081/pr.2014.5619 
520 |a In recent years, multidrug-resistant microorganisms appear as important nosocomial pathogens which treatment is quite difficult. As sufficient drug levels could not be achieved in cerebrospinal fluid during intravenous antibiotic therapy for central nervous system infections and due to multidrug-resistance treatment alternatives are limited. In this study, four cases of central nervous system infections due to multidrug-resistant microorganisms who were successfully treated with removal of the devices and intraventricular ciprofloxacin are presented. In conclusion, intraventricular ciprofloxacin can be used for treatment of central nervous system infections if the causative microorganism is sensitive to the drug and no other alternative therapy is available. 
546 |a EN 
690 |a intraventricular therapy, ciprofloxacin, children 
690 |a Medicine 
690 |a R 
690 |a Pediatrics 
690 |a RJ1-570 
655 7 |a article  |2 local 
786 0 |n Pediatric Reports, Vol 6, Iss 3 (2014) 
787 0 |n http://www.pagepress.org/journals/index.php/pr/article/view/5619 
787 0 |n https://doaj.org/toc/2036-749X 
787 0 |n https://doaj.org/toc/2036-7503 
856 4 1 |u https://doaj.org/article/0a6f42682cd94e4fa7c57f1749bb0515  |z Connect to this object online.