Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts

• Main Authors: Jagoda K Wrobel (Author), Sara Najafi (Author), Simay Ayhan (Author), Charlotte Gatzweiler (Author), Damir Krunic (Author), Johannes Ridinger (Author), Till Milde (Author), Frank Westermann (Author), Heike Peterziel (Author), Benjamin Meder (Author), Martin Distel (Author), Olaf Witt (Author), Ina Oehme (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The survival rate among children with relapsed neuroblastomas continues to be poor, and thus new therapeutic approaches identified by reliable preclinical drug testing models are urgently needed. Zebrafish are a powerful vertebrate model in preclinical cancer research. Here, we describe a zebrafish...