Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development

• Váldodahkkit: Nelly El-Sakkary (Dahkki), Steven Chen (Dahkki), Michelle R. Arkin (Dahkki), Conor R. Caffrey (Dahkki), Paula Ribeiro (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: The Company of Biologists, 2018-07-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Schistosomiasis is a tropical disease caused by a flatworm trematode parasite that infects over 200 million people worldwide. Treatment and control of the disease rely on just one drug, praziquantel. The possibility of drug resistance coupled with praziquantel's variable efficacy encourages the...