Emerging non-antibody‒drug conjugates (non-ADCs) therapeutics of toxins for cancer treatment

• Main Authors: Xiaolan Xu (Author), Jiaming Zhang (Author), Tao Wang (Author), Jing Li (Author), Yukang Rong (Author), Yanfang Wang (Author), Chenxia Bai (Author), Qing Yan (Author), Xiaohua Ran (Author), Yingli Wang (Author), Tianhong Zhang (Author), Jin Sun (Author), Qikun Jiang (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The non-selective cytotoxicity of toxins limits the clinical relevance of the toxins. In recent years, toxins have been widely used as warheads for antibody‒drug conjugates (ADCs) due to their efficient killing activity against various cancer cells. Although ADCs confer certain targeting properties...