Chemical composition and larvicidal activity of essential oils from Peganum harmala, Nepeta cataria and Phellodendron amurense against Aedes aegypti (Diptera: Culicidae)

Essential oils from aerial parts of the herbs Peganum harmala and Nepeta cataria, and leaves of the tree Phellodendron amurense were analyzed by GC-FID and GC-MS, and their larvicidal activities were assayed on the early fourth instar larvae of Aedes aegypti. The major constituents of the oils were...

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Main Authors: Shengxiang Yang (Author), Mingsheng Bai (Author), Jian Yang (Author), Yuan Yuan (Author), Yamei Zhang (Author), Jianchun Qin (Author), Yi Kuang (Author), Diego A. Sampietro (Author)
Format: Book
Published: Elsevier, 2020-05-01T00:00:00Z.
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Summary:Essential oils from aerial parts of the herbs Peganum harmala and Nepeta cataria, and leaves of the tree Phellodendron amurense were analyzed by GC-FID and GC-MS, and their larvicidal activities were assayed on the early fourth instar larvae of Aedes aegypti. The major constituents of the oils were limonene (14.5%) and thymol (11.5%) in P. harmala, thymol (46.5%), 4aα,7α,7aβ-nepetalactone (18.3%) and 4aα,7β,7aα-neptalactone (19.7%) in N. cataria, eugenol (14.5%) andγ-eudesmol (9.5%) in P. amurense.The oil of N. cataria had a strong larvicidal activity (LC50 < 50 µg/mL; LC90 < 86.8 µg/mL) on A. aegypti while the remaining oils showed a moderated killing effect. The larvicidal activity of N. cataria oil was associated to the contents of 1,8-cineol, camphor, 4aα,7α,7aβ-Nepetalactone, 4aα,7β,7aα-Nepetalactone and thymol. Our results indicate that the oil of N. catariadeserves to be used as a source of larvicidal agents against A. aegypti.
Item Description:1319-0164
10.1016/j.jsps.2020.03.007