Downregulation of tumor-suppressor gene LHX6 in cancer: a systematic review
Introduction. LIM Homeobox 6 (LHX6) encodes a LIM homeodomain transcription factor, contributes to tissue development and morphogenesis, and is mostly expressed in medial ganglionic eminence and odontogenic mesenchyme. However, it has been reported to play a role in cancer progression. This narrativ...
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Main Authors: | , , , , , , |
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Format: | Book |
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Sciendo,
2018-09-01T00:00:00Z.
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Summary: | Introduction. LIM Homeobox 6 (LHX6) encodes a LIM homeodomain transcription factor, contributes to tissue development and morphogenesis, and is mostly expressed in medial ganglionic eminence and odontogenic mesenchyme. However, it has been reported to play a role in cancer progression. This narrative review summarizes literatures that emphasize the molecular regulation of LHX6 in tumorigenesis. |
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Item Description: | 2501-062X 10.2478/rjim-2018-0008 |