The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis

• Main Authors: Jindong Xu (Author), William W. Du (Author), Nan Wu (Author), Feiya Li (Author), Xiangmin Li (Author), Yizhen Xie (Author), Sheng Wang (Author), Burton B. Yang (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doxorubicin is a chemotherapeutic medication commonly used to treat many types of cancers, but it has side effects including vomiting, rash, hair loss, and bone marrow suppression. The most dangerous side effects are cardiomyopathy, cardiofibrosis, and heart failure, as doxorubicin generates cytotox...