The Role and Mechanisms of Selenium Supplementation on Fatty Liver-Associated Disorder
Non-alcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease without effective therapy. Selenium, as an essential trace element for humans, is notable for its antioxidant properties. The previous study shows that selenium levels in NAFLD patients are lower than normal ones. S...
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| Format: | Book |
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MDPI AG,
2022-05-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_0b66af3f9de94a76b1011e4c40f28e45 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Lin Xu |e author |
| 700 | 1 | 0 | |a Yuanjun Lu |e author |
| 700 | 1 | 0 | |a Ning Wang |e author |
| 700 | 1 | 0 | |a Yibin Feng |e author |
| 245 | 0 | 0 | |a The Role and Mechanisms of Selenium Supplementation on Fatty Liver-Associated Disorder |
| 260 | |b MDPI AG, |c 2022-05-01T00:00:00Z. | ||
| 500 | |a 10.3390/antiox11050922 | ||
| 500 | |a 2076-3921 | ||
| 520 | |a Non-alcoholic fatty liver disease (NAFLD) is the most frequent chronic liver disease without effective therapy. Selenium, as an essential trace element for humans, is notable for its antioxidant properties. The previous study shows that selenium levels in NAFLD patients are lower than normal ones. Selenium supplementation can effectively alleviate metabolic disorders by relieving anti-oxidative stress and anti-inflammatory regulation. However, the correlation between selenium and NAFLD has not been fully clarified. Herein, we review the current studies on selenium in regulating the different stages of NAFLD and summarize relevant clinical trials to highlight the potential roles of selenium in NAFLD treatment. | ||
| 546 | |a EN | ||
| 690 | |a selenium | ||
| 690 | |a NAFLD | ||
| 690 | |a hepatic fibrosis | ||
| 690 | |a hepatocellular carcinoma | ||
| 690 | |a oxidant defense | ||
| 690 | |a inflammation | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Antioxidants, Vol 11, Iss 5, p 922 (2022) | |
| 787 | 0 | |n https://www.mdpi.com/2076-3921/11/5/922 | |
| 787 | 0 | |n https://doaj.org/toc/2076-3921 | |
| 856 | 4 | 1 | |u https://doaj.org/article/0b66af3f9de94a76b1011e4c40f28e45 |z Connect to this object online. |