Continual low-level MEK inhibition ameliorates cardio-facio-cutaneous phenotypes in zebrafish
SUMMARY Cardio-facio-cutaneous (CFC) syndrome is caused by germline mutations in KRAS, BRAF and MEK1/2. The highly selective and potent MEK inhibitors that have been developed as anti-cancer agents hold potential as therapeutics for CFC syndrome. We have previously shown that the effects of CFC muta...
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| Main Authors: | , , |
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| Format: | Book |
| Published: |
The Company of Biologists,
2012-07-01T00:00:00Z.
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