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The TH1902 Docetaxel Peptide-Drug Conjugate Inhibits Xenografts Growth of Human SORT1-Positive Ovarian and Triple-Negative Breast Cancer Stem-like Cells

<b>Background:</b> Breast and ovarian cancer stem cells (CSC) can contribute to the invasive and chemoresistance phenotype of tumors. TH1902, a newly developed sortilin (SORT1)-targeted peptide-docetaxel conjugate is currently in phase-1 clinical trial. Whether TH1902 impacts the chemore...

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Main Authors:	Michel Demeule (Author), Cyndia Charfi (Author), Jean-Christophe Currie (Author), Alain Zgheib (Author), Bogdan Alexandru Danalache (Author), Richard Béliveau (Author), Christian Marsolais (Author), Borhane Annabi (Author)
Format:	Book
Published:	MDPI AG, 2022-09-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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