CDK4/6 inhibitors in advanced breast cancer, what is beyond?

Resistant to hormonal treatment considered the main clinical challenge in the management of advanced breast cancer (ABC). The use of CDK4/6 inhibitors (CDK4/6I) may change the treatment landscape. In this mandated review, we will focus on the applicable role of CDK4/6I in the management of HR+/HER2-...

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Bibliographic Details
Main Authors: Amrallah A. Mohammed (Author), Hanaa Rashied (Author), Fifi Mostafa Elsayed (Author)
Format: Book
Published: Frontiers Media S.A., 2019-07-01T00:00:00Z.
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Summary:Resistant to hormonal treatment considered the main clinical challenge in the management of advanced breast cancer (ABC). The use of CDK4/6 inhibitors (CDK4/6I) may change the treatment landscape. In this mandated review, we will focus on the applicable role of CDK4/6I in the management of HR+/HER2- ABC, mechanisms of resistance, and promising future implementation.
Item Description:10.4081/oncol.2019.416
1970-5557
1970-5565