CDK4/6 inhibitors in advanced breast cancer, what is beyond?
Resistant to hormonal treatment considered the main clinical challenge in the management of advanced breast cancer (ABC). The use of CDK4/6 inhibitors (CDK4/6I) may change the treatment landscape. In this mandated review, we will focus on the applicable role of CDK4/6I in the management of HR+/HER2-...
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Frontiers Media S.A.,
2019-07-01T00:00:00Z.
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001 | doaj_0b9201e0cdba4c36892bca9c726d1cb8 | ||
042 | |a dc | ||
100 | 1 | 0 | |a Amrallah A. Mohammed |e author |
700 | 1 | 0 | |a Hanaa Rashied |e author |
700 | 1 | 0 | |a Fifi Mostafa Elsayed |e author |
245 | 0 | 0 | |a CDK4/6 inhibitors in advanced breast cancer, what is beyond? |
260 | |b Frontiers Media S.A., |c 2019-07-01T00:00:00Z. | ||
500 | |a 10.4081/oncol.2019.416 | ||
500 | |a 1970-5557 | ||
500 | |a 1970-5565 | ||
520 | |a Resistant to hormonal treatment considered the main clinical challenge in the management of advanced breast cancer (ABC). The use of CDK4/6 inhibitors (CDK4/6I) may change the treatment landscape. In this mandated review, we will focus on the applicable role of CDK4/6I in the management of HR+/HER2- ABC, mechanisms of resistance, and promising future implementation. | ||
546 | |a EN | ||
690 | |a Breast cancer | ||
690 | |a CDK4/6 inhibitors | ||
690 | |a predictors of response and resistance. | ||
690 | |a Other systems of medicine | ||
690 | |a RZ201-999 | ||
690 | |a Internal medicine | ||
690 | |a RC31-1245 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Oncology Reviews, Vol 13, Iss 2 (2019) | |
787 | 0 | |n https://www.oncologyreviews.org/index.php/or/article/view/416 | |
787 | 0 | |n https://doaj.org/toc/1970-5557 | |
787 | 0 | |n https://doaj.org/toc/1970-5565 | |
856 | 4 | 1 | |u https://doaj.org/article/0b9201e0cdba4c36892bca9c726d1cb8 |z Connect to this object online. |