Drug‐Disease Interaction and Time‐Dependent Population Pharmacokinetics of Isatuximab in Relapsed/Refractory Multiple Myeloma Patients

• Main Authors: Jean‐Baptiste Fau (Author), Raouf El‐Cheikh (Author), Claire Brillac (Author), Kimiko Koiwai (Author), Nathalie Mace (Author), Frank Campana (Author), Dorothee Semiond (Author), Laurent Nguyen (Author)
• Format: Bog
• Udgivet: Wiley, 2020-11-01T00:00:00Z.
• Fag: article
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Isatuximab, a monoclonal antibody (mAb) of immunoglobulin G (IgG) isotype, specifically targets the cluster of differentiation 38 antigen overexpressed in malignant plasma cells. Isatuximab is used to treat multiple myeloma (MM), characterized by the excessive production of abnormal "myeloma pr...