Zebrafish Larvae Are a Suitable Model to Investigate the Metabolic Phenotype of Drug-Induced Renal Tubular Injury

• Auteurs principaux: Judit Morello (Auteur), Rico J. E. Derks (Auteur), Susana S. Lopes (Auteur), Evelyne Steenvoorden (Auteur), Emilia C. Monteiro (Auteur), Oleg A. Mayboroda (Auteur), Sofia A. Pereira (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Prevention and treatment of drug-induced renal injury (DIRI) rely on the availability of sensitive and specific biomarkers of early kidney injury and predictive animal models of human pathophysiology. This study aimed to evaluate the potential of zebrafish larvae as translational model in metabolic...