Investigation of METTL3 as an inhibitor of kanamycin-induced ototoxicity via stress granule formation
BackgroundMethyltransferase-like 3 (METTL3), a component of the N6-methyladenosine (m6A) methyltransferase family, exhibits significant expression in HEI-OC1 cells and cochlear explants. Aminoglycoside antibiotics, known for their ototoxic potential, frequently induce irreversible auditory damage in...
Saved in:
Main Authors: | Yan Wu (Author), Yu-Yu Huang (Author), Lu-Yao Wang (Author), Yan Yang (Author), Fei-Lun Cui (Author), Shu-Na Li (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2024-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Kaixin-San improves Aβ-induced synaptic plasticity inhibition by affecting the expression of regulation proteins associated with postsynaptic AMPAR expression
by: Bo Zhang, et al.
Published: (2023) -
Current Strategies to Combat Cisplatin-Induced Ototoxicity
by: Dehong Yu, et al.
Published: (2020) -
Kanamycin and Cisplatin Ototoxicity: Differences in Patterns of Oxidative Stress, Antioxidant Enzyme Expression and Hair Cell Loss in the Cochlea
by: Alejandro Gibaja, et al.
Published: (2022) -
Apoptosis, autophagy, ferroptosis, and pyroptosis in cisplatin-induced ototoxicity and protective agents
by: Dingyuan Dai, et al.
Published: (2024) -
Dynamic Editome of Zebrafish under Aminoglycosides Treatment and Its Potential Involvement in Ototoxicity
by: Sijia Yan, et al.
Published: (2017)