Trisomy 19 and T(9;22) In a Patient with Acute Basophilic Leukemia
We report a case of acute basophilic leukemia with two coexisting clonal abnormalities, t(9;22) and trisomy 19. The blast showed positive reaction with myeloperoxidase but negative reaction with chloroacetate esterase and acid phosphatase. Metachromatic features of the blast were observed with tolui...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Hindawi Limited,
2011-01-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
|---|---|---|---|
| 001 | doaj_0c1f92c77bbb4b0b904d0da7b14d444c | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Alicia Rojas-Atencio |e author |
| 700 | 1 | 0 | |a Karelis Urdaneta |e author |
| 700 | 1 | 0 | |a Marisol Soto-Quintana |e author |
| 700 | 1 | 0 | |a Francisco Alvarez Nava |e author |
| 700 | 1 | 0 | |a Jenny Cañizales |e author |
| 700 | 1 | 0 | |a Ernesto Solis |e author |
| 245 | 0 | 0 | |a Trisomy 19 and T(9;22) In a Patient with Acute Basophilic Leukemia |
| 260 | |b Hindawi Limited, |c 2011-01-01T00:00:00Z. | ||
| 500 | |a 2090-6781 | ||
| 500 | |a 2090-679X | ||
| 500 | |a 10.1155/2011/269491 | ||
| 520 | |a We report a case of acute basophilic leukemia with two coexisting clonal abnormalities, t(9;22) and trisomy 19. The blast showed positive reaction with myeloperoxidase but negative reaction with chloroacetate esterase and acid phosphatase. Metachromatic features of the blast were observed with toluidine blue stain. Ultrastructure study showed the presence of azurophilic granules in basophils and blast mast cells. Conventional and molecular cytogenetic studies revealed, t(9;22) with BCR/ABL positive and trisomy 19 in all metaphase cells. To our knowledge, this paper here is the first to present acute basophilic leukemia with trisomy 19 and t(9;22). | ||
| 546 | |a EN | ||
| 690 | |a Pathology | ||
| 690 | |a RB1-214 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Case Reports in Pathology, Vol 2011 (2011) | |
| 787 | 0 | |n http://dx.doi.org/10.1155/2011/269491 | |
| 787 | 0 | |n https://doaj.org/toc/2090-6781 | |
| 787 | 0 | |n https://doaj.org/toc/2090-679X | |
| 856 | 4 | 1 | |u https://doaj.org/article/0c1f92c77bbb4b0b904d0da7b14d444c |z Connect to this object online. |