Cover Image

Review of the research on the influence of different functional substituents of new 1,2,4-triazole derivatives on the compounds biological properties

Today, 1,2,4-triazole derivatives are a promising class of organic compounds. This is caused, first of all, by the possibility of various chemical modifications of the 1,2,4-triazole fragment due to the addition of typical pharmacophores, which contributes to the expansion of the new molecules'...

Full description

Saved in:

Bibliographic Details
Main Authors:	M. V. Ogloblina (Author), I. V. Bushueva (Author), V. V. Parchenko (Author)
Format:	Book
Published:	The State Expert Center of the Ministry of Health of Ukraine, 2022-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Modern approaches to studying the antimicrobial and antifungal activities of new 1,2,4-triazole derivatives
by: M. V. Ogloblina, et al.
Published: (2022)

Analysis of biological properties of 1,2,4-triazole-containing compounds (literature review)
by: A. V. Khilkovets, et al.
Published: (2022)

Biological properties of the compounds formed by the combination of the 1,2,4-triazoles, furans and other functional substitutes
by: D. M. Danilchenko, et al.
Published: (2015)

Anticancer properties of 1,2,4-triazole derivatives (literature review)
by: I. V. Bushuieva, et al.
Published: (2024)

Physical-chemical properties of 5-(3-fluorophenyl)-4-amino-1,2,4-triazole-3-thiol s-derivatives
by: O. A. Bihdan, et al.
Published: (2017)

Synthesis and physical-chemical properties of some 5-(3-fluorophenyl)-4-methyl-1,2,4-triazole-3-thiol derivatives
by: O. A. Bihdan, et al.
Published: (2018)

Biological activity of the derivatives of 1,2,4-triazole
by: T. V. Kravchenko, et al.
Published: (2018)

The research of hepatoprotective activity in experimental hepatitis influenced by 1,2,4-triazole derivatives
by: I. M. Bilay, et al.
Published: (2014)

Some transformations in a series of 4-amino-1,2,4-triazole-3-thion derivatives
by: O. A. Bihdan, et al.
Published: (2024)

Pharmacological aspects of application of 1,2,4-triazole-3-thiol furan derivatives
by: O. A. Bihdan, et al.
Published: (2016)

Analysis of the domestic market of 1,2,4-triazole-containing drugs
by: M. V. Ohloblina, et al.
Published: (2022)

In silico study of new bis-3R, 4R'-5-(((1H-1,2,4-triazole-5-yl)thio)methyl)-4H-1,2,4-triazole-3-thione derivatives
by: Ye. O. Karpun, et al.
Published: (2019)

Heterocyclization reactions study of 3-thio and 3-thio-4-amino derivatives of 1,2,4-triazole
by: O. A. Bihdan, et al.
Published: (2017)

Biological features of new 1,2,4-triazole derivatives (a literature review)
by: M. V. Ohloblina
Published: (2022)

Physical and chemical properties of some 4-amino-5-(furan-2-, 2-metylfuran-3-yl)-1,2,4-triazole-3-thiol alkyl derivatives
by: D. M. Danilchenko, et al.
Published: (2016)

Chemical properties of amino- and thio-derivatives of 1,2,4-triazoles
by: A. G. Kaplaushenko
Published: (2015)

Computer prediction of toxicity of new S-alkyl derivatives of 1,2,4-triazole
by: V. V. Kalchenko, et al.
Published: (2024)

Diuretic activity of some 4- and 3-thio-substituted 1,2,4-triazoles with fluorophenyl fragments
by: O. A. Bihdan, et al.
Published: (2023)

The study of the optical activity of some S-derivatives 4-R-5-((((3-(pyridin-4-yl)-1H-1,2,4-triazole-5-yl)thio)methyl)-4H-1, 2,4-triazole-3-thiols
by: Ye. O. Karpun, et al.
Published: (2022)

The results of determining the indicators of the morphological composition of the blood of animals and individual biochemical indicators using a potential drug with a mixture of two active compounds: 4-((5-(decylthio)-4-methyl-4H-1,2,4-triazole-3-yl)methyl)morpholine and 5-(2-fluorophenyl)-4-((4-bromophenyl)ylidene)amino-1,2,4-triazole-3-thiol in milk thistle seed oil
by: M. V. Ohloblina, et al.
Published: (2022)

The search of new biologically active compounds with antibacterial and antifungal activity among 1,2,4-triazole-3-thiol derivatives with the remnants of thiophene
by: V. O. Salionov, et al.
Published: (2017)

Acute toxicity of 3-(2-, 3-fluorophenyl)-6-(aryl-, hetaryl)-[1,2,4]triazole[3,4-b][1,3,4]thiadiazoles
by: O. A. Bihdan, et al.
Published: (2017)

Antifatigue action of the 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thione alkyl derivatives
by: D. M. Danilchenko, et al.
Published: (2018)

Synthesis, physical-chemical properties and research of acute toxicity of 1,2,4-triazole derivatives containing thiophene core
by: V. A. Salionov
Published: (2015)

Synthesis and Biological Activities of Some 1,2,4-Triazole Derivatives: A Review
by: Dina Saleem M. Ameen, et al.
Published: (2022)

Synthesis and properties of some pyrazole derivatives of 1,2,4-triazole-3-thiol
by: A. S. Hotsulia, et al.
Published: (2020)

Investigation of physical and chemical properties of new derivatives of 5-(thiophene-3-ylmethyl)-4R-1,2,4-triazole-3-thiols
by: A. V. Khilkovets
Published: (2021)

Synthesis and antioxidant properties of new (2,4- and 3,4-dimethoxyphenyl)-1,2,4-triazoles
by: Dmitro V. Dovbnya, et al.
Published: (2022)

Evaluation of antioxidant activity of 1,2,4-triazole derivatives in the initiation of free radical processes
by: I. M. Bilai, et al.
Published: (2024)

Methods of synthesis of 1,2,4-triazole derivatives with methoxyphenyl and study the spectrum of their pharmacological activity
by: D. V. Dovbnia, et al.
Published: (2023)

Comparative pharmacokinetic study of dosage forms with morpholinium 2-[5-(pyridin-4-yl)-1,2,4-triazol-3-ylthio] acetate
by: I. V. Bushueva, et al.
Published: (2014)

Sodium 2-(4-amino-(5-(furan-2-yl)-1,2,4-triazole-3-ylthio)acetate, synthesis, study of biochemical indicators of blood serum cows in its use
by: D. M. Danilchenko, et al.
Published: (2017)

Synthesis and physical-chemical properties of 3-benzyl-8-(5-mercapto-4-phenyl-[1,2,4]-triazole-3-ylmethylthiomethyl)xanthine and its s-substituted derivatives
by: K. V. Аleksandrova, et al.
Published: (2015)

Synthesis and analgesic activity of new pyrazole-containing derivatives of 1,2,4-triazole-3-thiol
by: S. O. Fedotov, et al.
Published: (2023)

In vitro Biological Evaluation of 1,2,4-triazole Mannich Base
by: Mahmood Sherzad Rafaat, et al.
Published: (2023)

Synthesis and physicochemical properties 4-((R))amino)-5-methyl-4H-1,2,4-triazole-3-thiols
by: T. V. Kravchenko, et al.
Published: (2018)

Synthesis, structure and properties of some 5-R-4-phenyl-1,2,4-triazole-3-thiol derivatives
by: A. S. Hotsulia
Published: (2019)

The study of morpholinium 2-[5-(pyridin-4yl)-1,2,4-triazol-3-ylthio]acetate effect on prevention of stressful conditions
by: I. V. Bushueva, et al.
Published: (2014)

Synthesis and acute toxicity of new S-derivatives (1,2,4-triazole-3(2H)-yl)methyl) thiopyrimidines
by: Yu. V. Karpenko, et al.
Published: (2023)

In silico evaluation of the pharmacodynamic component of the interaction of S-alkyl derivatives of 5-methyl-4-(p-tolyl)-1,2,4-triazole-3-thiol with some biological targets
by: O. I. Panasenko, et al.
Published: (2023)