Preclinical pharmacokinetics, tissue distribution and plasma protein binding of sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (BZP), an innovative potent anti-ischemic stroke agent
Sodium (±)-5-bromo-2-(α-hydroxypentyl) benzoate (BZP) is a potential cardiovascular drug and exerts potent neuroprotective effect against transient and long-term ischemic stroke in rats. BZP could convert into 3-butyl-6-bromo-1(3H)-isobenzofuranone (Br-NBP) in vitro and in vivo. However, the pharmac...
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Main Authors: | Xin Tian (Author), Hongmeng Li (Author), Jingyao Wei (Author), Bingjie Liu (Author), Yuhai Zhang (Author), Gaoju Wang (Author), Junbiao Chang (Author), Hailing Qiao (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2016-08-01T00:00:00Z.
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