Applicability of a Modified Rat Model of Acute Arthritis for Long-Term Testing of Drug Delivery Systems

• Main Authors: Imke Rudnik-Jansen (Author), Nina Woike (Author), Suzanne de Jong (Author), Sabine Versteeg (Author), Marja Kik (Author), Pieter Emans (Author), George Mihov (Author), Jens Thies (Author), Niels Eijkelkamp (Author), Marianna Tryfonidou (Author), Laura Creemers (Author)
• Format: Book
• Published: MDPI AG, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Episodes of inflammation and pain are predominant features of arthritic joint diseases. Drug delivery systems (DDS) could reduce inflammation and pain long-term without chances of infection upon multiple injections. To allow for long-term evaluation of DDS, we modified a previously published acute a...