Impaired histone deacetylases 5 and 6 expression mimics the effects of obesity and hypoxia on adipocyte function

• Main Authors: Julien Bricambert (Author), Dimitri Favre (Author), Saška Brajkovic (Author), Amélie Bonnefond (Author), Raphael Boutry (Author), Roberto Salvi (Author), Valérie Plaisance (Author), Mohamed Chikri (Author), Giulia Chinetti-Gbaguidi (Author), Bart Staels (Author), Vittorio Giusti (Author), Robert Caiazzo (Author), François Pattou (Author), Gérard Waeber (Author), Philippe Froguel (Author), Amar Abderrahmani (Author)
• Format: Book
• Published: Elsevier, 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The goal of the study was to investigate the role of histone deacetylases (HDACs) in adipocyte function associated with obesity and hypoxia. Methods: Total proteins and RNA were prepared from human visceral adipose tissues (VAT) of human obese and normal weight subjects and from white adi...