Congenital Dengue Infection: A Novel Case of vertical transmission of Dengue virus in Karachi, Pakistan

Abstract: Introduction: Dengue is a systemic viral infection that is generally transmitted among humans through female mosquito bite. However there are other modes of transmission as well but very little is known about them due to infrequent reporting. This article reports a case of vertical transmi...

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Main Authors: Shumaila Shabbir (Author), Shaista Ehsan (Author)
Format: Book
Published: ziauddin University, 2024-05-01T00:00:00Z.
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100 1 0 |a Shumaila Shabbir  |e author 
700 1 0 |a Shaista Ehsan  |e author 
245 0 0 |a Congenital Dengue Infection: A Novel Case of vertical transmission of Dengue virus in Karachi, Pakistan 
260 |b ziauddin University,   |c 2024-05-01T00:00:00Z. 
500 |a 10.36283/PJMD10-3/017 
500 |a 2313-7371 
500 |a 2308-2593 
520 |a Abstract: Introduction: Dengue is a systemic viral infection that is generally transmitted among humans through female mosquito bite. However there are other modes of transmission as well but very little is known about them due to infrequent reporting. This article reports a case of vertical transmission of dengue virus in Karachi, Pakistan. Case presentation: A male newborn who was born with normal weight and normal Apgar score developed fever on 8th day of his life. The fever progressed through an erythromatous skin rash which appeared on 3rd day of initial symptom. There was no evidence of mosquito exposure to the baby after the birth. However the baby's mother gave a history of mosquito bites two days prior to her delivery. The mother had also developed fever on 7th day of delivery and a maculopapular rash during her 9th postpartum day.  Baseline investigations of the neonate showed thrombocytopenia, anemia and raised liver function markers. Dengue NS1 antigen test through ELISA was done in both mother and the baby. The test results turned out positive in both the mother and the infant. The diagnosis of dengue fever was established. This case report demonstrates the possibility of the vertical transmission of dengue. Conclusion: The health care providers should be aware of this mode of transmission and should be trained adequately to handle such cases. Keywords: Dengue; Congenital; Vertical transmission; Platelets 
546 |a EN 
690 |a Dengue; Congenital; Vertical transmission; Platelets 
690 |a Biochemistry 
690 |a QD415-436 
690 |a Dentistry 
690 |a RK1-715 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
690 |a Medicine (General) 
690 |a R5-920 
655 7 |a article  |2 local 
786 0 |n Pakistan Journal of Medicine and Dentistry, Vol 10, Iss 3 (2024) 
787 0 |n https://ojs.zu.edu.pk/pjmd/article/view/979 
787 0 |n https://doaj.org/toc/2313-7371 
787 0 |n https://doaj.org/toc/2308-2593 
856 4 1 |u https://doaj.org/article/0cfbd8b6843c43e2892904173d5a59ec  |z Connect to this object online.