Adiponectin attenuates angiotensin II-induced vascular smooth muscle cell remodeling through nitric oxide and the RhoA/ROCK pathway.

• Main Authors: Wared eNour-Eldine (Author), Crystal M eGhantous (Author), Kazem eZibara (Author), Leila eDib (Author), Hawra eIssa (Author), Hana Ahmad Itani (Author), Nabil eEl-Zein (Author), Asad eZeidan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

INTRODUCTION: Adiponectin (APN), an adipocytokine, exerts protective effects on cardiac remodeling, while angiotensin II (Ang II) induces hypertension and vascular remodeling. The potential protective role of APN on the vasculature during hypertension has not been fully elucidated yet. Here, we eval...