Renal and cardiovascular morbidities associated with APOL1 among African American and Non-African American children with focal segmental glomerulosclerosis.

• Main Authors: Robert P Woroniecki (Author), Derek Ng (Author), Sophie Limou (Author), Cheryl A Winkler (Author), Kimberly Jean Reidy (Author), Mark Mitsnefes (Author), Matthew G Sampson (Author), Craig S Wong (Author), Bradley A Warady (Author), Susan L Furth (Author), Jeffrey B Kopp (Author), Frederick Jeffrey Kaskel (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and objectives: African American (AA) children with focal segmental glomerulosclerosis (FSGS) have later onset disease that progresses more rapidly than in non-AA children. It is unclear how APOL1 genotypes contribute to kidney disease risk, progression and cardiovascular morbidity in chi...