Pharmacokinetic comparison of sitagliptin and metformin HCl extended-release tablets versus JANUMET® XR in healthy volunteers under fasting and fed conditions

• Main Authors: Linling Que (Author), Wei Qin (Author), Yunfei Shi (Author), Ying Ding (Author), Kai Huang (Author), Zhenzhong Qian (Author), Bingjie Huang (Author), Peipei Zhou (Author), Qing He (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Objectives: Janumet® XR is the combination of sitagliptin and extended metformin hydrochloride produced by Merck Sharp & Dohme. It is specially designed for diabetes mellitus patients taking both drugs already. Janumet® XR exhibited clinically significant blood glucose lowering ef...