Association of inflammation, dyslipidemia, obesity and physical activity status in children

• Main Authors: Juliano Magalhães Guedes (Author), José Bontempo Mamêde Neto (Author), Alynne Christian Ribeiro Andaki (Author), Patrícia Feliciano Pereira (Author), Michelle Dias de Oliveira (Author), Roberto Sousa Dias (Author), Sérgio Oliveira de Paula (Author), Antônio José Natali (Author), Alexandre de Paula Rogério (Author), Edmar Lacerda Mendes (Author)
• Format: Book
• Published: Universidade Estadual Paulista (UNESP), 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Abstract The aim of this study was to verify the association between inflammatory biomarkers, dyslipidemia, obesity and physical activity status in 10-years old children. Ninety-four children participated in this study and were classified into eutrophic (n=36), overweight (n=34) or obese (n=24) according to their body mass index (BMI). The genic expression of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α) and chemokine C-C motif ligand 2 (CCL-2) mRNA; the serum concentration of high-density lipoprotein cholesterol (HDL-c) and triglycerides; BMI, percentage of body fat (% BF) and waist circumference; and the number of steps per day were determined. The expression of IL-6, TNF-α and CCL-2 were associated (p < 0.05) positively with serum triglycerides, BMI, % BF and waist circumference, and negatively with serum HDL-c. No association (p > 0.05) between pro-inflammatory biomarkers and number of steps per day was found.

Item Description

1980-6574
10.1590/S1980-6574201600020003