HLA and proteasome expression body map

• Main Authors: Sebastian Boegel (Author), Martin Löwer (Author), Thomas Bukur (Author), Patrick Sorn (Author), John C. Castle (Author), Ugur Sahin (Author)
• Format: Book
• Published: BMC, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The presentation of HLA peptide complexes to T cells is a highly regulated and tissue specific process involving multiple transcriptionally controlled cellular components. The extensive polymorphism of HLA genes and the complex composition of the proteasome make it difficult to m...