Overexpression of a Mycobacterium ulcerans Ag85B-EsxH Fusion Protein in Recombinant BCG Improves Experimental Buruli Ulcer Vaccine Efficacy.

Buruli ulcer (BU) vaccine design faces similar challenges to those observed during development of prophylactic tuberculosis treatments. Multiple BU vaccine candidates, based upon Mycobacterium bovis BCG, altered Mycobacterium ulcerans (MU) cells, recombinant MU DNA, or MU protein prime-boosts, have...

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Main Authors: Bryan E Hart (Author), Sunhee Lee (Author)
Format: Book
Published: Public Library of Science (PLoS), 2016-12-01T00:00:00Z.
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3rd Floor Main Library

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