Effect of <it>BRCA2 </it>sequence variants predicted to disrupt exonic splice enhancers on <it>BRCA2 </it>transcripts

• Main Authors: Brewster Brooke L (Author), Pettigrew Christopher A (Author), Whiley Phillip J (Author), Walker Logan C (Author), Spurdle Amanda B (Author), Brown Melissa A (Author)
• פורמט: ספר
• יצא לאור: BMC, 2010-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Genetic screening of breast cancer patients and their families have identified a number of variants of unknown clinical significance in the breast cancer susceptibility genes, <it>BRCA1 </it>and <it>BRCA2</it>...