AKR1B1-Induced Epithelial-Mesenchymal Transition Mediated by RAGE-Oxidative Stress in Diabetic Cataract Lens
Purpose: Cataracts are a major cause of visual acuity deterioration in diabetes mellitus (DM) in developed and developing countries. Studies have demonstrated that overproduction of AKR1B1 and receptor for advanced glycation end products (RAGE) plays a major role in the pathogenesis of diabetic cata...
Saved in:
Main Authors: | Tsung-Tien Wu (Author), Ying-Ying Chen (Author), Hui-Yu Chang (Author), Ya-Hsin Kung (Author), Ching-Jiunn Tseng (Author), Pei-Wen Cheng (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2020-03-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus
by: Tsung-Tien Wu, et al.
Published: (2021) -
The interaction between autophagy and the epithelial-mesenchymal transition mediated by NICD/ULK1 is involved in the formation of diabetic cataracts
by: Jiyuan Ma, et al.
Published: (2022) -
Enzymes of the AKR1B and AKR1C subfamilies and uterine diseases
by: Tea eLanisnik Rizner
Published: (2012) -
Noncoding RNAs in Tumor Epithelial-to-Mesenchymal Transition
by: Ching-Wen Lin, et al.
Published: (2016) -
Expression of the Aldo-Keto Reductases AKR1B1 and AKR1B10 in Human Cancers.
by: Brian eLaffin, et al.
Published: (2012)