Discovery of N-Containing (-)-Borneol Esters as Respiratory Syncytial Virus Fusion Inhibitors

• Main Authors: Anastasiya S. Sokolova (Author), Olga I. Yarovaya (Author), Lana V. Kuzminykh (Author), Anna A. Shtro (Author), Artem M. Klabukov (Author), Anastasia V. Galochkina (Author), Yulia V. Nikolaeva (Author), Galina D. Petukhova (Author), Sophia S. Borisevich (Author), Edward M. Khamitov (Author), Nariman F. Salakhutdinov (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-11-01T00:00:00Z.
• Fag: article
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Respiratory syncytial virus (RSV) causes acute respiratory infections, thus, posing a serious threat to the health of infants, children, and elderly people. In this study, we have discovered a series of potent RSV entry inhibitors with the (-)-borneol scaffold. The active compounds <b>3b</b...